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This solution is made according to USP specifications and for use in drug dissolution studies.

Simulated Intestinal and Gastric fluids

Simulated Intestinal and Gastric fluids

The solutions are made according to USP methods for dissolution testing

Simulated Intestinal and Gastric Fluids

Imitation of gastrointestinal conditions is necessary for dissolution and pharmacokinetic studies of drug formulations. Dissolution is a routine part of Quality Control testing for most medications and dissolution methods, including required medium, are specified by Pharmacopeia monographs. The use of appropriate dissolution media during drug development stage also helps answer questions on bioavailability of the pharmaceuticals. Simulated gastric and intestinal fluids are also used to study the safety profile of products that carry risks of unintended use like accidental ingestion. 

Simulated Intestinal Fluid and Simulated Gastric Fluid test solutions are prepared according to USP specifications. We offer these products with and without enzymes to accommodate different USP testing requirements. Our 2-part formulations come with dry pre-weighted enzyme powder to be mixed in before use. This allows for longer shelf life of the product and predictable activity of the enzyme in solution. 

Stabilized Simulated Intestinal Fluid contains preservative to prevent bacterial growth and can be stored at room temperature.

Simulated Intestinal and Gastric Fluids

Catalog No. Description Qty
1700-0900 USP Simulated Gastric Fluid, without enzyme, each (950 mL/bottle) each (950 mL/bottle)
1700-0902 USP Simulated Gastric Fluid, with enzyme, 2-part, each (950 mL/bottle) each (950 mL/bottle)
1700-0903 USP Simulated Intestinal Fluid, with enzyme, 2-part, each (950 mL/bottle) each (950 mL/bottle)
1700-0904 USP Simulated Intestinal Fluid, w/o enzyme, Not Stabilized, each (950 mL/bottle) each (950 mL/bottle)
1700-0905 USP Simulated Intestinal Fluid, w/o enzyme, Stabilized, each (950 mL/bottle) each (950 mL/bottle)